I think there are a couple drivers that will allow 5V PWM, but you need to figure out which LEDs you plan to use first. Since LEDs are rated by current, the driver needs to match. 700-750mA seems to be a good goal. Although many Crees are rated up to 1.5A, I'd look for the nominal rating and go with that. The LEDs will run cooler and last longer.
With a constant current driver, you don't need a resistor or fuse in a series-only circuit. The driver adjusts automatically if a short or open occurs.
Parallel circuits are another matter, and I'd advise against them if you aren't intimately familiar with them. Each branch needs a specific resistor based on both resistance and wattage needs. The resistor protects against cascading parallel branch failures if one branch "dies", forcing the remaining current through the other branches, exceeding their rated current, and causing yet another branch to fail. It's a real PITA if you haven't designed the circuit correctly.
With a constant current driver, you don't need a resistor or fuse in a series-only circuit. The driver adjusts automatically if a short or open occurs.
Parallel circuits are another matter, and I'd advise against them if you aren't intimately familiar with them. Each branch needs a specific resistor based on both resistance and wattage needs. The resistor protects against cascading parallel branch failures if one branch "dies", forcing the remaining current through the other branches, exceeding their rated current, and causing yet another branch to fail. It's a real PITA if you haven't designed the circuit correctly.